Monday, October 17, 2016

Journal article "The Effects of External Compression on Venous Blood Flow and Tissue Deformation in the Lower Leg"

This is a discussion of the journal article "The Effects of External Compression on Venous Blood Flow and Tissue Deformation in the Lower Leg" by Dai et al.  A co-author on this paper is Roger Kamm who has done extensive work on flow modeling of the venous system.

The journal article may be accessed at reseachgate.net at this link: 
https://www.researchgate.net/profile/Roger_Kamm/publication/12681713_The_Effects_of_External_Compression_on_Venous_Blood_Flow_and_Tissue_Deformation_in_the_Lower_Leg/links/0fcfd51236d6adf190000000.pdf

The article uses FEA (finite element analysis) to model venous flow and vein collapse when symmetric and asymmetric compression is applied. 
  A few important points that I have identified are the following:
1. The elastic modulus of skin is 2 x 10^6 Pa.  The elastic modulus of the fascia is 3.4 x 10^8 Pa.  Elastic modulus is the material's resistance to deformation (not permanent deformation). This means that skin is much more easily deformed than fascia.   

2. Asymmetric compression more effectively narrows the vein diameter than symmetric circumferential compression.  



From Fig. 4 of the article, for the same amount of compression, for example, 30 mmHg, asymmetric compression (designated as Anterior-Posterior Compression) effectively collapses the vein whereas circumferentially-uniform compression at 30 mmHg leaves the vein relatively open. 

3. Because asymmetric compression more effectively narrows the vein diameter, the blood flow velocity is higher with asymmetric compression. 

From Fig. 7 of the article, asymmetric compression causes a higher flow velocity peak than symmetric compression (as determined at the thigh location).  The article also looks at single versus two-compartment graded-sequential compression (Fig. 7 bottom plot).  There also, asymmetric compression shows a higher flow velocity.  Surprisingly, the two-compartment, graded-sequential pressure application does not show a higher flow velocity than a single chamber pressure application.  This suggests single-chamber compression devices are adequate.  

The article suggests that an effective compression device should deliver asymmetric (not uniform circumferential) compression and multi/gradient compression chambers may not be necessary.  









1 comment:

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